Category: Herzschwäche

Study: Heart Failure Acute effects of vitamin C on platelet responsiveness to nitric oxide donors and endothelial function in patients with chronic heart failure. Ellis GR; Anderson RA; Chirkov YY; Morris-Thurgood J; Jackson SK; Lewis MJ; Horowitz JD; Frenneaux MP Journal of Cardiovascular Pharmacology 2001 May;37(5):564-70 Chronic heart failure (CHF) is characterized by a prothrombotic […] More

Study: Heart Failure Dietary and blood antioxidants in patients with chronic heart failure. Insights into the potential importance of selenium in heart failure. de Lorgeril M; Salen P; Accominotti M; Cadau M; Steghens JP; Boucher F; de Leiris J European Journal of Heart Failure 2001 Dec;3(6):661-9 BACKGROUND: Chronic heart failure (CHF) seems to be associated […] More

Study: Heart Failure L-carnitine treatment for congestive heart failure–experimental and clinical study. Kobayashi A; Masumura Y; Yamazaki N Japanese Circulation Journal 1992 Jan;56(1):86-94 To evaluate the therapeutic efficacy of l-carnitine in heart failure, the myocardial carnitine levels and the therapeutic efficacy of l-carnitine were studied in cardiomyopathic BIO 14.6 hamsters and in patients with chronic […] More

Study: Heart Failure A randomised, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction. Singh RB; Niaz MA; Agarwal P; Beegum R; Rastogi SS; Sachan DS Postgraduate Medical Journal 1996 Jan;72(843):45-50 In a randomised, double-blind placebo-controlled trial, the effects of the administration of oral L-carnitine (2 g/day) for 28 days were compared in the […] More

Study: Heart Failure Controlled study on the therapeutic efficacy of propionyl-L-carnitine in patients with congestive heart failure. Mancini M; Rengo F; Lingetti M; Sorrentino GP; Nolfe G Arzneimittelforschung 1992 Sep;42(9):1101-4 A double-blind phase II study of propionyl-L-carnitine (CAS 17298-37-2) versus placebo was carried out on a group of 60 patients with mild to moderate (II […] More

Study: Heart Failure Acute and chronic effects of propionyl-L-carnitine on the hemodynamics, exercise capacity, and hormones in patients with congestive heart failure. Anand I; Chandrashekhan Y; De Giuli F; Pasini E; Mazzoletti A; Confortini R; Ferrari R Cardiovasc Drugs Ther 1998 Jul;12(3):291-9 Carnitine is an important cofactor in the intermediary metabolism of the heart, and […] More

Study: Heart Failure Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure (interim analysis). The CoQ10 Drug Surveillance Investigators. Baggio E; Gandini R; Plancher AC; Passeri M; Carmosino G Clinical Investigation 1993;71(8 Suppl):S145-9 Digitalis, diuretics, and vasodilators are considered standard therapy for patients with congestive heart failure, […] More

Study: Heart Failure Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study. Morisco C; Trimarco B; Condorelli M Clinical Investigation 1993;71(8 Suppl):S134-6 The improved cardiac function in patients with congestive heart failure treated with coenzyme Q10 supports the hypothesis that this condition is characterized by mitochondrial dysfunction and […] More

Study: Heart Failure Perspectives on therapy of cardiovascular diseases with coenzyme Q10 (ubiquinone). Mortensen SA Clinical Investigation 1993;71(8 Suppl):S116-23 A defective myocardial energy supply–due to lack of substrates and/or essential cofactors and a poor utilization efficiency of oxygen–may be a common final pathway in the progression of myocardial diseases of various etiologies. The vitamin-like essential […] More

Study: Heart Failure Treatment of congestive heart failure with coenzyme Q10 illuminated by meta-analyses of clinical trials. Soja AM; Mortensen SA Molecular Aspects of Medicine 1997;18 Suppl:S159-68 The purpose of this was to investigate the effect of coenzyme Q10 (CoQ10) in patients with congestive heart failure (CHF) by measuring the possible improvement of certain relevant […] More