Kategorie: Arthritis


  • Glaxo Patent on Kratom from 1970 found only „Minimal side effects…in contrast to Codeine“

    The pharmaceutical company Glaxo Smith Kline blocked potential Kratom products by competitors with a prohibitiv patent in 1970. Nothing special because this blocking strategy is pretty much standart procedure for producers of patented pharmaceuticals. The patent prooves that at least Glaxo Smith Kline knows since nearly 50 years about Kratoms only „minimal side effects“ compared […] More

  • Glucosamine sulfate, Chondroitin sulfate

    Study: Glucosamine sulfate, Chondroitin sulfate „GAG for osteoarthritis of the knee–a prospective study“ Debi R; Robinson D; Agar G; Halperin N; Harefuah 2000 Mar 15;138(6):451-3, 518. Osteoarthritis results from progressive catabolic loss of cartilage proteoglycans due to imbalance between synthesis and degradation. The availability of glucosamine, an intermediate in mucopolysaccharide synthesis, can be rate-limiting for […] More

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  • Glucosamine sulfate, Chondroitin sulfate

    Study: Glucosamine sulfate, Chondroitin sulfate „Anti-arthrosis treatments: efficacy and tolerance of chondroitin sulfates (CS 4&6)“ Conrozier T; Presse Med 1998 Nov 21;27(36):1862-5. CHONDROPROTECTIVE DRUGS: Long-acting chondroprotective drugs have a symptomatic effect. They are only effective in subjects with osteoarthritis and have no pure pain relieving effect. They act within several weeks, improve functional manifestations and […] More

  • Niacinamide

    Study: Niacinamide „The effect of niacinamide on osteoarthritis: a pilot study.“ Jonas WB; Rapoza CP; Blair WF; Inflamm Res 1996 Jul;45(7):330-4. ABSTRACT: OBJECTIVE: To evaluate the effect of niacinamide, on selected parameters of osteoarthritis using a double-blind, placebo controlled study design. METHODS: Seventy two patients with osteoarthritis were randomized for treatment with niacinamide or an […] More

  • Vitamin E

    Study: Vitamin E „High dosage therapy in patients with activated arthrosis“ VERNACULAR TITLE: Hochdosierte Vitamin-E-Therapie bei Patienten mit aktivierter Arthrose. Scherak O; Kolarz G; Schodl C; Blankenhorn G; Z Rheumatol 1990 Nov-Dec;49(6):369-73. ABSTRACT: The known antiphlogistic in vitro effect of vitamin E was tested in a double-blind randomized study in patients with osteoarthritis. Fifty-three in-patients […] More

  • Vitamin E, Osteoarthritis

    Study: Vitamin E, Osteoarthritis „Tocopherol in Osteoarthritis: a controlled pilot study.“ Machtey I; Ouaknine L; J Am Geriatr Soc 1978 Jul;26(7):328-30. ABSTRACT: Thirty-two patients entered a simple-blind, cross-over study on the action of tocopherol in osteoarthritis; only 3 did not complete the course. Each patient was randomly assigned either to the tocopherol group (600 mg/day […] More

  • Tranexamic acid

    Study: Tranexamic acid „Tranexamic acid, an inhibitor of plasminogen activation, reduces urinary collagen cross-link excretion in both experimental and rheumatoid arthritis.“ Ronday HK; Te Koppele JM; Greenwald RA; Moak SA; De Roos JA; Dijkmans BA; Breedveld FC; Verheijen JH; Br J Rheumatol 1998 Jan;37(1):34-8. ABSTRACT: The plasminogen activation system is one of the enzyme systems […] More

  • Rheumatoid arthritis, Oxidant/antioxidant status

    Study: Rheumatoid arthritis, Oxidant/antioxidant status „Oxidant/antioxidant status of plasma samples from patients with rheumatoid arthritis.“ Ozturk HS; Cimen MY; Cimen OB; Kacmaz M; Durak I; Rheumatol Int 1999;19(1-2):35-7. ABSTRACT: This study aims to elucidate plasma oxidant/antioxidant status in patients with rheumatoid arthritis (RA). Fasting blood samples were obtained from 24 patients with RA and 20 […] More

  • Juvenile rheumatoid arthritis, Oxidant-antioxidant imbalance

    Study: Juvenile rheumatoid arthritis, Oxidant-antioxidant imbalance „Oxidant-antioxidant imbalance in blood of children with juvenile rheumatoid arthritis.“ Araujo V; Arnal C; Boronat M; Ruiz E; Dominguez C; Biofactors 1998;8(1-2):155-9 ABSTRACT: Juvenile rheumatoid arthritis (JRA) is the most commonly diagnosed rheumatic disease in children and may represent not a single disease, but rather a syndrome of diverse […] More

  • Rheumatoid arthritis, Selenium

    Study: Rheumatoid arthritis, Selenium „Selenium concentration in erythrocytes of patients with rheumatoid arthritis. Clinical and laboratory chemistry infection markers during administration of selenium.“ VERNACULAR TITLE: Selenkonzentration in den Erythrozyten bei Patienten mit rheumatoider Arthritis. Klinische und laborchemische Entzündungszeichen unter Supplementierung mit Selen. Heinle K; Adam A; Gradl M; Wiseman M; Adam O; Med Klin 1997 […] More